Posted by & filed under Ingredients.

t Essential Wholesale, we get a lot of questions about ingredients. People want to know what they are, how they are extracted from plant materials or created in a lab, what they are used for and how to use them. Good thing we have this blog and our resident cosmetics expert Laura Craig to share all the information you need to decide which ingredients will perform best in your products.


One of the ingredients we receive questions on the most is DMAE, which is short for dimethylaminoethanol, a naturally occurring substance that facilitates the synthesis of the neurotransmitter acetylcholine. DMAE also may stimulate the synthesis of phosphatidylcholine, an important component of cell membranes. DMAE is more of a "smart drug" than a skin firming agent. In a number of studies, DMAE has been shown to reduce age-related deterioration in cognitive ability and memory.

The DMAE World, According To Laura

Some studies show that DMAE reduces the accumulation of lipofuscin deposits inside cells. Lipofuscin is a cellular pigment made up of aggregated chunks of molecular waste. It tends to occur in the cells of older people. It is likely that lipofuscin is not simply a byproduct of aging but also contributes to the aging process. The neurons, heart and skin of older people usually contain particularly large amounts of lipofiscin. So this is why DMAE is awesome as an oral supplement and it corresponds with my philosophy that "if it’s good for you internally, then it’s good for you externally.

Our skin is, in my opinion, the most fascinating organ. It actually does absorb things we put on it, as well as acts as a shield for other things. DMAE has been demonstrated to cause some degree of skin tightening. However, despite speculation, it remains unclear how DMAE firms the skin – whether by stabilizing the membranes, boosting acetylcholine, reducing lipofuscin deposits or none of the above. Whatever the mechanism, the effect of DMAE is often noticeable although seldom dramatic. Besides, even though DMAE can’t reverse existing facial sag, it may reduce its progression. Some people report a cumulative effect with continued use of DMAE.  The way I think DMAE works for our skin is the same way it is shown to work in our brains. I think it’s "reminding" our skin of the way it used to be.

DMAE is a major ingredient in the Ultimate Serum. I have used the Ultimate Facial Serum for almost 4 years and having had cystic acne most of my life; my pores were larger than average. After a while, I started getting bored and decided to try some other company’s serum that said it was "wrinkle reducing, Vitamin C Rich" and would take years off my life. It happened to smell incredible, so for $35 for 1 oz, I purchased it.

The next morning, I excitedly put on my lovely smelling serum, followed it with my foundation and went to work. Two hours later it appeared that my skin was sliding off my face. My foundation was falling off my face and my pores looked like I had shoved basketballs into them! I made some excuse about not having drunk enough water and proceeded to use the same serum the following day. Well needless to say, I did not have to bother with "third time’s a charm", as I never used that serum after the second day. I went back to Essential Wholesale serums and my skin is still thanking me.

People are always shocked when I tell them about my past acne trials, since there is barely any evidence of scarring, or the large pores and divots that such severe acne normally leaves behind. Now, is it the DMAE alone in the Ultimate Facial Serum that made the difference for my skin, or is it the combination of the ingredients? Well, I can’t honestly say, except that the DMAE & MSM Serum is my new favorite serum as the MSM is really softening my skin and my pores are still saying "thank you." So, draw your own personal conclusions.



One Response to “Laura Answers Your Questions About DMAE”

  1. Nancy

    I am trying out the serums and currently favor the ultimate. When using the dmae/msm serum i find it feels sticky and hot on my skin. I am wondering about the use of vegetable glycerin in all of the serums and other creams. What purpose doe it serve? I think it may be the sticky culprit, since ia am aware of its other uses when i was showing horses on a national/World level. We used it on the horses necks, wrapped them with blanket to cause sweating and induce a sleeker looking appearance. It got very warm and was very sticky stuff.Nancy